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Genetic polymorphisms in lung disease: bandwagon or breakthrough?

The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to identify persons at risk for pulmonary disease and to predict treatment response. Several pitfalls are commonl...

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Detalles Bibliográficos
Autores principales: Iannuzzi, Michael C, Maliarik, Mary, Rybicki, Benjamin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC107844/
https://www.ncbi.nlm.nih.gov/pubmed/11980584
http://dx.doi.org/10.1186/rr164
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author Iannuzzi, Michael C
Maliarik, Mary
Rybicki, Benjamin
author_facet Iannuzzi, Michael C
Maliarik, Mary
Rybicki, Benjamin
author_sort Iannuzzi, Michael C
collection PubMed
description The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to identify persons at risk for pulmonary disease and to predict treatment response. Several pitfalls are commonly encountered in studying genetic polymorphisms, and this article points out criteria that should be applied to design high-quality genetic polymorphism studies.
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spelling pubmed-1078442002-05-09 Genetic polymorphisms in lung disease: bandwagon or breakthrough? Iannuzzi, Michael C Maliarik, Mary Rybicki, Benjamin Respir Res Review The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to identify persons at risk for pulmonary disease and to predict treatment response. Several pitfalls are commonly encountered in studying genetic polymorphisms, and this article points out criteria that should be applied to design high-quality genetic polymorphism studies. BioMed Central 2002 2002-02-19 /pmc/articles/PMC107844/ /pubmed/11980584 http://dx.doi.org/10.1186/rr164 Text en Copyright © 2002 BioMed Central Ltd
spellingShingle Review
Iannuzzi, Michael C
Maliarik, Mary
Rybicki, Benjamin
Genetic polymorphisms in lung disease: bandwagon or breakthrough?
title Genetic polymorphisms in lung disease: bandwagon or breakthrough?
title_full Genetic polymorphisms in lung disease: bandwagon or breakthrough?
title_fullStr Genetic polymorphisms in lung disease: bandwagon or breakthrough?
title_full_unstemmed Genetic polymorphisms in lung disease: bandwagon or breakthrough?
title_short Genetic polymorphisms in lung disease: bandwagon or breakthrough?
title_sort genetic polymorphisms in lung disease: bandwagon or breakthrough?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC107844/
https://www.ncbi.nlm.nih.gov/pubmed/11980584
http://dx.doi.org/10.1186/rr164
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