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Differential modulation of microglia superoxide anion and thromboxane B(2 )generation by the marine manzamines
BACKGROUND: Thromboxane B(2 )(TXB(2)) and superoxide anion (O(2)(-)) are neuroinflammatory mediators that appear to be involved in the pathogenesis of several neurodegenerative diseases. Because activated-microglia are the main source of TXB(2 )and O(2)(- )in these disorders, modulation of their syn...
Autores principales: | Mayer, Alejandro MS, Hall, Mary L, Lynch, Sean M, Gunasekera, Sarath P, Sennett, Susan H, Pomponi, Shirley A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1079881/ https://www.ncbi.nlm.nih.gov/pubmed/15762999 http://dx.doi.org/10.1186/1471-2210-5-6 |
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