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Inhibition of archaeal growth and DNA topoisomerase VI activities by the Hsp90 inhibitor radicicol
Type II DNA topoisomerases have been classified into two families, Topo IIA and Topo IIB, based on structural and mechanistic dissimilarities. Topo IIA is the target of many important antibiotics and antitumoural drugs, most of them being inactive on Topo IIB. The effects and mode of action of Topo...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1084324/ https://www.ncbi.nlm.nih.gov/pubmed/15849317 http://dx.doi.org/10.1093/nar/gki526 |