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Evaluation of the VP22 protein for enhancement of a DNA vaccine against anthrax

BACKGROUND: Previously, antigens expressed from DNA vaccines have been fused to the VP22 protein from Herpes Simplex Virus type I in order to improve efficacy. However, the immune enhancing mechanism of VP22 is poorly understood and initial suggestions that VP22 can mediate intercellular spread have...

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Detalles Bibliográficos
Autores principales:	Perkins, Stuart D, Flick-Smith, Helen C, Garmory, Helen S, Essex-Lopresti, Angela E, Stevenson, Freda K, Phillpotts, Robert J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087864/ https://www.ncbi.nlm.nih.gov/pubmed/15842732 http://dx.doi.org/10.1186/1479-0556-3-3

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