Potential cellular receptors involved in hepatitis C virus entry into cells

Hepatitis C virus (HCV) infects hepatocytes and leads to permanent, severe liver damage. Since the genomic sequence of HCV was determined, progress has been made towards understanding the functions of the HCV-encoded proteins and identifying the cellular receptor(s) responsible for adsorption and pe...

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Detalles Bibliográficos
Autores principales: Favre, Daniel, Muellhaupt, Beat
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087871/
https://www.ncbi.nlm.nih.gov/pubmed/15836798
http://dx.doi.org/10.1186/1476-511X-4-9
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author Favre, Daniel
Muellhaupt, Beat
author_facet Favre, Daniel
Muellhaupt, Beat
author_sort Favre, Daniel
collection PubMed
description Hepatitis C virus (HCV) infects hepatocytes and leads to permanent, severe liver damage. Since the genomic sequence of HCV was determined, progress has been made towards understanding the functions of the HCV-encoded proteins and identifying the cellular receptor(s) responsible for adsorption and penetration of the virus particle into the target cells. Several cellular receptors for HCV have been proposed, all of which are associated with lipid and lipoprotein metabolism. This article reviews the cellular receptors for HCV and suggests a general model for HCV entry into cells, in which lipoproteins play a crucial role.
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spelling pubmed-10878712005-04-30 Potential cellular receptors involved in hepatitis C virus entry into cells Favre, Daniel Muellhaupt, Beat Lipids Health Dis Review Hepatitis C virus (HCV) infects hepatocytes and leads to permanent, severe liver damage. Since the genomic sequence of HCV was determined, progress has been made towards understanding the functions of the HCV-encoded proteins and identifying the cellular receptor(s) responsible for adsorption and penetration of the virus particle into the target cells. Several cellular receptors for HCV have been proposed, all of which are associated with lipid and lipoprotein metabolism. This article reviews the cellular receptors for HCV and suggests a general model for HCV entry into cells, in which lipoproteins play a crucial role. BioMed Central 2005-04-19 /pmc/articles/PMC1087871/ /pubmed/15836798 http://dx.doi.org/10.1186/1476-511X-4-9 Text en Copyright © 2005 Favre and Muellhaupt; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Favre, Daniel
Muellhaupt, Beat
Potential cellular receptors involved in hepatitis C virus entry into cells
title Potential cellular receptors involved in hepatitis C virus entry into cells
title_full Potential cellular receptors involved in hepatitis C virus entry into cells
title_fullStr Potential cellular receptors involved in hepatitis C virus entry into cells
title_full_unstemmed Potential cellular receptors involved in hepatitis C virus entry into cells
title_short Potential cellular receptors involved in hepatitis C virus entry into cells
title_sort potential cellular receptors involved in hepatitis c virus entry into cells
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087871/
https://www.ncbi.nlm.nih.gov/pubmed/15836798
http://dx.doi.org/10.1186/1476-511X-4-9
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AT muellhauptbeat potentialcellularreceptorsinvolvedinhepatitiscvirusentryintocells

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