Thyroid hormone receptor binding to DNA and T(3)-dependent transcriptional activation are inhibited by uremic toxins

BACKGROUND: There is a substantial clinical overlap between chronic renal failure (CRF) and hypothyroidism, suggesting the presence of hypothyroidism in uremic patients. Although CRF patients have low T(3 )and T(4 )levels with normal thyroid-stimulating hormone (TSH), they show a higher prevalence o...

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Detalles Bibliográficos
Autores principales: Santos, Guilherme M, Pantoja, Carlos J, Costa e Silva, Aluízio, Rodrigues, Maria C, Ribeiro, Ralff C, Simeoni, Luiz A, Lomri, Noureddine, Neves, Francisco AR
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087878/
https://www.ncbi.nlm.nih.gov/pubmed/15807894
http://dx.doi.org/10.1186/1478-1336-3-1

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