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CD34+ cells cultured in stem cell factor and interleukin-2 generate CD56+ cells with antiproliferative effects on tumor cell lines
In vitro stimulation of CD34+ cells with IL-2 induces NK cell differentiation. In order to define the stages of NK cell development, which influence their generation from CD34 cells, we cultured G-CSF mobilized peripheral blood CD34+ cells in the presence of stem cell factor and IL-2. After three we...
Autores principales: | Sconocchia, Giuseppe, Provenzano, Maurizio, Rezvani, Katayoun, Li, Jongming, Melenhorst, Jos, Hensel, Nancy, Barrett, A John |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1087889/ https://www.ncbi.nlm.nih.gov/pubmed/15831091 http://dx.doi.org/10.1186/1479-5876-3-15 |
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