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XRCC1 is required for DNA single-strand break repair in human cells
The X-ray repair cross complementing 1 (XRCC1) protein is required for viability and efficient repair of DNA single-strand breaks (SSBs) in rodents. XRCC1-deficient mouse or hamster cells are hypersensitive to DNA damaging agents generating SSBs and display genetic instability after such DNA damage....
Autores principales: | Brem, Reto, Hall, Janet |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088068/ https://www.ncbi.nlm.nih.gov/pubmed/15867196 http://dx.doi.org/10.1093/nar/gki543 |
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