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XRCC1 is required for DNA single-strand break repair in human cells

The X-ray repair cross complementing 1 (XRCC1) protein is required for viability and efficient repair of DNA single-strand breaks (SSBs) in rodents. XRCC1-deficient mouse or hamster cells are hypersensitive to DNA damaging agents generating SSBs and display genetic instability after such DNA damage....

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Detalles Bibliográficos
Autores principales: Brem, Reto, Hall, Janet
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088068/
https://www.ncbi.nlm.nih.gov/pubmed/15867196
http://dx.doi.org/10.1093/nar/gki543

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