Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells

Interactions between B and T cells are essential for most antibody responses, but the dynamics of these interactions are poorly understood. By two-photon microscopy of intact lymph nodes, we show that upon exposure to antigen, B cells migrate with directional preference toward the B-zone–T-zone boun...

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Detalles Bibliográficos
Autores principales: Okada, Takaharu, Miller, Mark J, Parker, Ian, Krummel, Matthew F, Neighbors, Margaret, Hartley, Suzanne B, O'Garra, Anne, Cahalan, Michael D, Cyster, Jason G
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088276/
https://www.ncbi.nlm.nih.gov/pubmed/15857154
http://dx.doi.org/10.1371/journal.pbio.0030150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088276/
https://www.ncbi.nlm.nih.gov/pubmed/15857154
http://dx.doi.org/10.1371/journal.pbio.0030150

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