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Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells
Interactions between B and T cells are essential for most antibody responses, but the dynamics of these interactions are poorly understood. By two-photon microscopy of intact lymph nodes, we show that upon exposure to antigen, B cells migrate with directional preference toward the B-zone–T-zone boun...
Autores principales: | Okada, Takaharu, Miller, Mark J, Parker, Ian, Krummel, Matthew F, Neighbors, Margaret, Hartley, Suzanne B, O'Garra, Anne, Cahalan, Michael D, Cyster, Jason G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088276/ https://www.ncbi.nlm.nih.gov/pubmed/15857154 http://dx.doi.org/10.1371/journal.pbio.0030150 |
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