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In situ oligonucleotide synthesis on poly(dimethylsiloxane): a flexible substrate for microarray fabrication
In this paper, we demonstrate in situ synthesis of oligonucleotide probes on poly(dimethylsiloxane) (PDMS) microchannels through use of conventional phosphoramidite chemistry. PDMS polymer was moulded into a series of microchannels using standard soft lithography (micro-moulding), with dimensions &l...
Autores principales: | Moorcroft, Matthew J., Meuleman, Wouter R. A., Latham, Steven G., Nicholls, Thomas J., Egeland, Ryan D., Southern, Edwin M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1088307/ https://www.ncbi.nlm.nih.gov/pubmed/15870385 http://dx.doi.org/10.1093/nar/gni075 |
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