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Human physiologically based pharmacokinetic model for propofol

BACKGROUND: Propofol is widely used for both short-term anesthesia and long-term sedation. It has unusual pharmacokinetics because of its high lipid solubility. The standard approach to describing the pharmacokinetics is by a multi-compartmental model. This paper presents the first detailed human ph...

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Detalles Bibliográficos
Autores principales: Levitt, David G, Schnider, Thomas W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1090550/
https://www.ncbi.nlm.nih.gov/pubmed/15847680
http://dx.doi.org/10.1186/1471-2253-5-4