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The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II
During transcription by RNA polymerase (RNAP) II, the incoming ribonucleoside triphosphate (NTP) enters the catalytic center in association with an Mg(2+) ion, termed metal B [Mg(B)]. When bound to RNAP II, Mg(B) is coordinated by the β and γ phosphates of the NTP, Rpb1 residues D481 and D483 and Rp...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2005
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1092279/ https://www.ncbi.nlm.nih.gov/pubmed/15886393 http://dx.doi.org/10.1093/nar/gki570 |