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GABA(A )receptor γ2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines

BACKGROUND: Gamma-aminobutyric acid type A receptors (GABA(A)-Rs) are the major inhibitory receptors in the mammalian brain and are modulated by a number of sedative/hypnotic drugs including benzodiazepines and anesthetics. The significance of specific GABA(A)-Rs subunits with respect to behavior an...

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Detalles Bibliográficos
Autores principales:	Chandra, Dev, Korpi, Esa R, Miralles, Celia P, De Blas, Angel L, Homanics, Gregg E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1097738/ https://www.ncbi.nlm.nih.gov/pubmed/15850489 http://dx.doi.org/10.1186/1471-2202-6-30

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