N-acetyl-L-cysteine ameliorates the inflammatory disease process in experimental autoimmune encephalomyelitis in Lewis rats

We report that N-acetyl-L-cysteine (NAC) treatment blocked induction of TNF-α, IL-1β, IFN-γ and iNOS in the CNS and attenuated clinical disease in the myelin basic protein induced model of experimental allergic encephalomyelitis (EAE) in Lewis rats. Infiltration of mononuclear cells into the CNS and...

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Detalles Bibliográficos
Autores principales: Stanislaus, Romesh, Gilg, Anne G, Singh, Avtar K, Singh, Inderjit
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1097751/
https://www.ncbi.nlm.nih.gov/pubmed/15869713
http://dx.doi.org/10.1186/1740-2557-2-4

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