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ZAC, LIT1 (KCNQ1OT1) and p57(KIP2) (CDKN1C) are in an imprinted gene network that may play a role in Beckwith–Wiedemann syndrome
Loss of genomic imprinting is involved in a number of developmental abnormalities and cancers. ZAC is an imprinted gene expressed from the paternal allele of chromosome 6q24 within a region known to harbor a tumor suppressor gene for several types of neoplasia. p57(KIP2) (CDKN1C) is a maternally exp...
Autores principales: | Arima, Takahiro, Kamikihara, Tetsuya, Hayashida, Toshirou, Kato, Kiyoko, Inoue, Toshiaki, Shirayoshi, Yasuaki, Oshimura, Mitsuo, Soejima, Hidenobu, Mukai, Tunehiro, Wake, Norio |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1097765/ https://www.ncbi.nlm.nih.gov/pubmed/15888726 http://dx.doi.org/10.1093/nar/gki555 |
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