Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit

The efficiency of programmed ribosomal frameshifting in decoding antizyme mRNA is the sensor for an autoregulatory circuit that controls cellular polyamine levels in organisms ranging from the yeast Schizosaccharomyces pombe to Drosophila to mammals. Comparison of the frameshift sites and flanking s...

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Detalles Bibliográficos
Autores principales: Ivanov, Ivaylo P., Gesteland, Raymond F., Atkins, John F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2000
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC110703/
https://www.ncbi.nlm.nih.gov/pubmed/10954585
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author Ivanov, Ivaylo P.
Gesteland, Raymond F.
Atkins, John F.
author_facet Ivanov, Ivaylo P.
Gesteland, Raymond F.
Atkins, John F.
author_sort Ivanov, Ivaylo P.
collection PubMed
description The efficiency of programmed ribosomal frameshifting in decoding antizyme mRNA is the sensor for an autoregulatory circuit that controls cellular polyamine levels in organisms ranging from the yeast Schizosaccharomyces pombe to Drosophila to mammals. Comparison of the frameshift sites and flanking stimulatory signals in many organisms now permits a reconstruction of the likely evolutionary path of the remarkably conserved mRNA sequences involved in the frameshifting.
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spelling pubmed-1107032002-08-15 Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit Ivanov, Ivaylo P. Gesteland, Raymond F. Atkins, John F. Nucleic Acids Res Survey and Summary The efficiency of programmed ribosomal frameshifting in decoding antizyme mRNA is the sensor for an autoregulatory circuit that controls cellular polyamine levels in organisms ranging from the yeast Schizosaccharomyces pombe to Drosophila to mammals. Comparison of the frameshift sites and flanking stimulatory signals in many organisms now permits a reconstruction of the likely evolutionary path of the remarkably conserved mRNA sequences involved in the frameshifting. Oxford University Press 2000-09-01 /pmc/articles/PMC110703/ /pubmed/10954585 Text en Copyright © 2000 Oxford University Press
spellingShingle Survey and Summary
Ivanov, Ivaylo P.
Gesteland, Raymond F.
Atkins, John F.
Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit
title Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit
title_full Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit
title_fullStr Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit
title_full_unstemmed Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit
title_short Antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit
title_sort antizyme expression: a subversion of triplet decoding, which is remarkably conserved by evolution, is a sensor for an autoregulatory circuit
topic Survey and Summary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC110703/
https://www.ncbi.nlm.nih.gov/pubmed/10954585
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AT gestelandraymondf antizymeexpressionasubversionoftripletdecodingwhichisremarkablyconservedbyevolutionisasensorforanautoregulatorycircuit
AT atkinsjohnf antizymeexpressionasubversionoftripletdecodingwhichisremarkablyconservedbyevolutionisasensorforanautoregulatorycircuit

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