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Differential clinical efficacy of anti-CD4 monoclonal antibodies in rat adjuvant arthritis is paralleled by differential influence on NF-κB binding activity and TNF-α secretion of T cells

The aim of this study was to analyze the differential effects of three anti-CD4 monoclonal antibodies (mAbs) (with distinct epitope specifities) in the treatment of rat adjuvant arthritis (AA) and on T-cell function and signal transduction. Rat AA was preventively treated by intraperitoneal injectio...

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Detalles Bibliográficos
Autores principales:	Pohlers, Dirk, Schmidt-Weber, Carsten B, Franch, Angels, Kuhlmann, Jürgen, Bräuer, Rolf, Emmrich, Frank, Kinne, Raimund W
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111020/ https://www.ncbi.nlm.nih.gov/pubmed/12010568

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