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Melatonin reduces TNF-a induced expression of MAdCAM-1 via inhibition of NF-kB.

BACKGROUND: Endothelial MAdCAM-1 (mucosal addressin cell adhesion molecule-1) expression is associated with the oxidant-dependent induction and progress of inflammatory bowel disease (IBD). Melatonin, a relatively safe, potent antioxidant, has shown efficacy in several chronic injury models may limi...

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Detalles Bibliográficos
Autores principales:	Sasaki, Makoto, Jordan, Paul, Joh, Takashi, Itoh, Makotoh, Jenkins, Michael, Pavlick, Kevin, Minagar, Alireza, Alexander, Steven J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111062/ https://www.ncbi.nlm.nih.gov/pubmed/12003644 http://dx.doi.org/10.1186/1471-230X-2-9

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