Glycerol restores heat-induced p53-dependent apoptosis of human glioblastoma cells bearing mutant p53

BACKGROUND: We have previously reported that glycerol acts as a chemical chaperone to restore the expression of WAF1 in some human cancer cell lines bearing mutant p53. Since the expression of WAF1 is up-regulated by activated wildtype p53, glycerol appears to restore wtp53 function. The aim of the...

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Detalles Bibliográficos
Autores principales: Ohnishi, Takeo, Ohnishi, Ken, Takahashi, Akihisa
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111188/
https://www.ncbi.nlm.nih.gov/pubmed/11965244
http://dx.doi.org/10.1186/1472-6750-2-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111188/
https://www.ncbi.nlm.nih.gov/pubmed/11965244
http://dx.doi.org/10.1186/1472-6750-2-6

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