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Clade, Country and Region-specific HIV-1 Vaccines: Are they necessary?

Today, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a unique vaccine for every world region or virus subtype may not be necessary.

Detalles Bibliográficos
Autores principales: Slobod, Karen S, Coleclough, Chris, Brown, Scott A, Stambas, John, Zhan, Xiaoyan, Surman, Sherri, Jones, Bart G, Zirkel, Amy, Freiden, Pamela J, Brown, Brita, Sealy, Robert, Bonsignori, Mattia, Hurwitz, Julia L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1112584/
https://www.ncbi.nlm.nih.gov/pubmed/15860130
http://dx.doi.org/10.1186/1742-6405-2-3
Descripción
Sumario:Today, scientists are often encouraged to custom-design vaccines based on a particular country or clade. Here, we review the scientific literature and then suggest that the overwhelming endeavor to produce a unique vaccine for every world region or virus subtype may not be necessary.