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Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria
We report the first in vitro and genetic confirmation of Malarone(®) (GlaxoSmithKline; atovaquone and proguanil hydrochloride) resistance in Plasmodium falciparum acquired in Africa. On presenting with malaria two weeks after returning from a 4-week visit to Lagos, Nigeria without prophylaxis, a mal...
Autores principales: | Fivelman, Quinton L, Butcher, Geoffrey A, Adagu, Ipemida S, Warhurst, David C, Pasvol, Geoffrey |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC111499/ https://www.ncbi.nlm.nih.gov/pubmed/12057021 http://dx.doi.org/10.1186/1475-2875-1-1 |
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