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Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model

BACKGROUND: Gene transfer studies in primary T cells have suffered from the limitations of conventional viral transduction or transfection techniques. Replication-defective adenoviral vectors are an attractive alternative for gene delivery. However, naive lymphocytes are not readily susceptible to i...

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Detalles Bibliográficos
Autores principales: Hurez, Vincent, Dzialo-Hatton, Robin, Oliver, James, Matthews, R James, Weaver, Casey T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC113271/
https://www.ncbi.nlm.nih.gov/pubmed/12019030
http://dx.doi.org/10.1186/1471-2172-3-4