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Kinetic analysis of the role of the tyrosine 13, phenylalanine 56 and glutamine 54 network in the U1A/U1 hairpin II interaction
The A protein of the U1 small nuclear ribonucleoprotein particle, interacting with its stem–loop RNA target (U1hpII), is frequently used as a paradigm for RNA binding by recognition motif domains (RRMs). U1A/U1hpII complex formation has been proposed to consist of at least two steps: electrostatical...
Autores principales: | Law, Michael J., Chambers, Eric J., Katsamba, Phinikoula S., Haworth, Ian S., Laird-Offringa, Ite A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140079/ https://www.ncbi.nlm.nih.gov/pubmed/15914668 http://dx.doi.org/10.1093/nar/gki602 |
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