A novel transgenic chimaeric mouse system for the rapid functional evaluation of genes encoding secreted proteins

A major challenge of the post-genomic era is the functional characterization of anonymous open reading frames (ORFs) identified by the Human Genome Project. In this context, there is a strong requirement for the development of technologies that enhance our ability to analyze gene functions at the le...

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Detalles Bibliográficos
Autores principales: Kakitani, Makoto, Oshima, Takeshi, Horikoshi, Kaori, Yoshitome, Tetsuo, Ueda, Akiko, Kajikawa, Miwa, Iba, Yumi, Ozone, Yoshinao, Ijima, Yuki, Yoshino, Tohko, Itoh, Mikiko, Seki, Sachiko, Aoki, Ayako, Ishihara, Toshie, Shionoya, Michiyo, Makino, Utako, Kitada, Rina, Ohguma, Atsuko, Ohta, Takami, Yoshida, Yoshimasa, Kudoh, Hiroe, Hanaoka, Kazunori, Sibuya, Kazunori, Ishida, Isao, Kakeda, Minoru, Yagi, Mikio, Yoneya, Takashi, Tomizuka, Kazuma
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140086/
https://www.ncbi.nlm.nih.gov/pubmed/15914664
http://dx.doi.org/10.1093/nar/gni083

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