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A versatile reducible polycation-based system for efficient delivery of a broad range of nucleic acids
Synthetic vectors based on reducible polycations consisting of histidine and polylysine residues (HIS RPCs) were evaluated for their ability to deliver nucleic acids. Initial experiments showed that RPC-based vectors with at least 70% histidine content mediated efficient levels of gene transfer with...
Autores principales: | Read, Martin L., Singh, Surjeet, Ahmed, Zubair, Stevenson, Mark, Briggs, Simon S., Oupicky, David, Barrett, Lee B., Spice, Rachel, Kendall, Mark, Berry, Martin, Preece, Jon A., Logan, Ann, Seymour, Leonard W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140087/ https://www.ncbi.nlm.nih.gov/pubmed/15914665 http://dx.doi.org/10.1093/nar/gni085 |
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