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Processing of Pre-microRNAs by the Dicer-1–Loquacious Complex in Drosophila Cells

microRNAs (miRNAs) are a large family of 21- to 22-nucleotide non-coding RNAs that interact with target mRNAs at specific sites to induce cleavage of the message or inhibit translation. miRNAs are excised in a stepwise process from primary miRNA (pri-miRNA) transcripts. The Drosha-Pasha/DGCR8 comple...

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Detalles Bibliográficos
Autores principales: Saito, Kuniaki, Ishizuka, Akira, Siomi, Haruhiko, Siomi, Mikiko C
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1141268/
https://www.ncbi.nlm.nih.gov/pubmed/15918769
http://dx.doi.org/10.1371/journal.pbio.0030235