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Characterisation and application of a bovine U6 promoter for expression of short hairpin RNAs

BACKGROUND: The use of small interfering RNA (siRNA) molecules in animals to achieve double-stranded RNA-mediated interference (RNAi) has recently emerged as a powerful method of sequence-specific gene knockdown. As DNA-based expression of short hairpin RNA (shRNA) for RNAi may offer some advantages...

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Detalles Bibliográficos
Autores principales:	Lambeth, Luke S, Moore, Robert J, Muralitharan, Morley, Dalrymple, Brian P, McWilliam, Sean, Doran, Timothy J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142307/ https://www.ncbi.nlm.nih.gov/pubmed/15885150 http://dx.doi.org/10.1186/1472-6750-5-13

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