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CYP3A4 and CYP3A5 genotyping by Pyrosequencing

BACKGROUND: Human cytochrome P450 3A enzymes, particularly CYP3A4 and CYP3A5, play an important role in drug metabolism. CYP3A expression exhibits substantial interindividual variation, much of which may result from genetic variation. This study describes Pyrosequencing assays for key SNPs in CYP3A4...

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Detalles Bibliográficos
Autores principales:	Garsa, Adam A, McLeod, Howard L, Marsh, Sharon
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142317/ https://www.ncbi.nlm.nih.gov/pubmed/15882469 http://dx.doi.org/10.1186/1471-2350-6-19

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