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UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein

Upstream of N-ras (Unr) has been described as an internal initiation trans-acting factor (ITAF) in the cap-independent translation of some particular viral and cellular mRNAs. Two factors led us to hypothesize that the UNR 5′-untranslated region (5′-UTR) may contain an internal ribosome entry site (...

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Detalles Bibliográficos
Autores principales: Cornelis, Sigrid, Tinton, Sandrine A., Schepens, Bert, Bruynooghe, Yanik, Beyaert, Rudi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142345/
https://www.ncbi.nlm.nih.gov/pubmed/15928332
http://dx.doi.org/10.1093/nar/gki611

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