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UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein
Upstream of N-ras (Unr) has been described as an internal initiation trans-acting factor (ITAF) in the cap-independent translation of some particular viral and cellular mRNAs. Two factors led us to hypothesize that the UNR 5′-untranslated region (5′-UTR) may contain an internal ribosome entry site (...
Autores principales: | Cornelis, Sigrid, Tinton, Sandrine A., Schepens, Bert, Bruynooghe, Yanik, Beyaert, Rudi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142345/ https://www.ncbi.nlm.nih.gov/pubmed/15928332 http://dx.doi.org/10.1093/nar/gki611 |
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