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Cell-type-specific epigenetic marking of the IL2 gene at a distal cis-regulatory region in competent, nontranscribing T-cells
T-cells retain cell-type-specific programming for IL-2 inducibility through many rounds of division without being stimulated to transcribe the locus. To understand the layering of controls needed to poise this gene heritably for activation, we have used chromatin immunoprecipitation to map histone m...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2005
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142491/ https://www.ncbi.nlm.nih.gov/pubmed/15937196 http://dx.doi.org/10.1093/nar/gki637 |