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Mammary stem cells, self-renewal pathways, and carcinogenesis
The mammary gland epithelial components are thought to arise from stem cells that undergo both self-renewal and differentiation. Self-renewal has been shown to be regulated by the Hedgehog, Notch, and Wnt pathways and the transcription factor B lymphoma Mo-MLV insertion region 1 (Bmi-1). We review d...
Autores principales: | Liu, Suling, Dontu, Gabriela, Wicha, Max S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143566/ https://www.ncbi.nlm.nih.gov/pubmed/15987436 http://dx.doi.org/10.1186/bcr1021 |
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