Cargando…

Phosphorylation of human oxoguanine DNA glycosylase (α-OGG1) modulates its function

Oxoguanine DNA glycosylase (OGG1) initiates the repair of 8-oxoguanine (8-oxoG), a major oxidative DNA base modification that has been directly implicated in cancer and aging. OGG1 functions in the base excision repair pathway, for which a molecular hand-off mechanism has been proposed. To date, onl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Jingping, Imam, Syed Z., Hashiguchi, Kazunari, de Souza-Pinto, Nadja C., Bohr, Vilhelm A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143695/ https://www.ncbi.nlm.nih.gov/pubmed/15942030 http://dx.doi.org/10.1093/nar/gki636

Ejemplares similares

Expression of 8-oxoguanine DNA glycosylase (Ogg1) in mouse retina
por: Bigot, Karine, et al.
Publicado: (2009)

Lost in the Crowd: How Does Human 8-Oxoguanine DNA Glycosylase 1 (OGG1) Find 8-Oxoguanine in the Genome?
por: D’Augustin, Ostiane, et al.
Publicado: (2020)

8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction
por: Sampath, Harini, et al.
Publicado: (2012)

An active alternative splicing isoform of human mitochondrial 8-oxoguanine DNA glycosylase (OGG1)
por: Furihata, Chie
Publicado: (2015)

8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Exacerbates Doxorubicin-Induced Cardiac Dysfunction
por: Anene-Nzelu, Chukwuemeka George, et al.
Publicado: (2022)

8-Oxoguanine targeted by 8-oxoguanine DNA glycosylase 1 (OGG1) is central to fibrogenic gene activation upon lung injury
por: Pan, Lang, et al.
Publicado: (2023)

Structural Features of the Interaction between Human 8-Oxoguanine DNA Glycosylase hOGG1 and DNA
por: Koval, V. V., et al.
Publicado: (2014)

Synthetic Routes to N-9 Alkylated 8-Oxoguanines; Weak Inhibitors of the Human DNA Glycosylase OGG1
por: Mahajan, Tushar R., et al.
Publicado: (2015)

8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle
por: Vartanian, Vladimir, et al.
Publicado: (2017)

Substrate-specific binding of 8-oxoguanine DNA glycosylase 1 (OGG1) reprograms mucosal adaptations to chronic airway injury
por: Pan, Lang, et al.
Publicado: (2023)

The Role of 8-Oxoguanine DNA Glycosylase-1 in Inflammation
por: Ba, Xueqing, et al.
Publicado: (2014)

Thermodynamic and kinetic basis for recognition and repair of 8-oxoguanine in DNA by human 8-oxoguanine-DNA glycosylase
por: Kirpota, Oleg O., et al.
Publicado: (2011)

Functional Characterization of 8-Oxoguanine DNA Glycosylase of Trypanosoma cruzi
por: Furtado, Carolina, et al.
Publicado: (2012)

8-Oxoguanine DNA Glycosylases: One Lesion, Three Subfamilies
por: Faucher, Frédérick, et al.
Publicado: (2012)

Kinetics of substrate recognition and cleavage by human 8-oxoguanine-DNA glycosylase
por: Kuznetsov, Nikita A., et al.
Publicado: (2005)

8-Oxoguanine DNA Glycosylase (OGG1) Cys326 Variant: Increased Risk for Worse Outcome of Patients with Locally Advanced Rectal Cancer after Multimodal Therapy
por: Leu, Martin, et al.
Publicado: (2021)

Epigenetic control of type III interferon expression by 8-oxoguanine and its reader 8-oxoguanine DNA glycosylase1
por: Xue, Yaoyao, et al.
Publicado: (2023)

The mechanism of the glycosylase reaction with hOGG1 base-excision repair enzyme: concerted effect of Lys249 and Asp268 during excision of 8-oxoguanine
por: Šebera, Jakub, et al.
Publicado: (2017)

Thermodynamics of the DNA Damage Repair Steps of Human 8-Oxoguanine DNA Glycosylase
por: Kuznetsov, Nikita A., et al.
Publicado: (2014)

Deletion of OGG1 Results in a Differential Signature of Oxidized Purine Base Damage in mtDNA Regions
por: Chimienti, Guglielmina, et al.
Publicado: (2019)

The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase
por: Shigdel, Uddhav K., et al.
Publicado: (2020)

Molecular beacons with oxidized bases report on substrate specificity of DNA oxoguanine glycosylases
por: Sun, Jingjing, et al.
Publicado: (2022)

Effects of the stimuli-dependent enrichment of 8-oxoguanine DNA glycosylase1 on chromatinized DNA
por: Hao, Wenjing, et al.
Publicado: (2018)

A Novel Role for the DNA Repair Enzyme 8-Oxoguanine DNA Glycosylase in Adipogenesis
por: Komakula, Sai Santosh Babu, et al.
Publicado: (2021)

8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions
por: Ba, Xueqing, et al.
Publicado: (2017)

8-Oxoguanine DNA Glycosylase 1 Upregulation as a Risk Factor for Obesity and Colorectal Cancer
por: Pilo, Jesús, et al.
Publicado: (2023)

OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence
por: De Rosa, Mariarosaria, et al.
Publicado: (2023)

Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing
por: Franck, Coste, et al.
Publicado: (2022)

Absence of the DNA repair enzyme human 8-oxoguanine glycosylase is associated with an aggressive breast cancer phenotype
por: Karihtala, P, et al.
Publicado: (2012)

The Potential Role of 8-Oxoguanine DNA Glycosylase-Driven DNA Base Excision Repair in Exercise-Induced Asthma
por: Belanger, KarryAnne K., et al.
Publicado: (2016)

Human 8-oxoguanine DNA glycosylase increases resistance to hyperoxic cytotoxicity in lung epithelial cells and involvement with altered MAPK activity
por: Kannan, S, et al.
Publicado: (2005)

Protective association exhibited by the single nucleotide polymorphism (SNP) rs1052133 in the gene human 8-oxoguanine DNA glycosylase (hOGG1) with the risk of squamous cell carcinomas of the head & neck (SCCHN) among north Indians
por: Mitra, Amit Kumar, et al.
Publicado: (2011)

Triphlorethol-A from Ecklonia cava Up-Regulates the Oxidant Sensitive 8-Oxoguanine DNA Glycosylase 1
por: Kim, Ki Cheon, et al.
Publicado: (2014)

A thermophilic 8-oxoguanine DNA glycosylase from Thermococcus barophiluss Ch5 is a new member of AGOG DNA glycosylase family : Biochemical and functional characterization of archaeal 8oxoG DNA glycosylase
por: Wang, Lei, et al.
Publicado: (2022)

Significant Contribution of DNA Repair Human 8-Oxoguanine DNA N-Glycosylase 1 Genotypes to Renal Cell Carcinoma
por: Chang, Wen-Shin, et al.
Publicado: (2020)

Effect of DNA Glycosylases OGG1 and Neil1 on Oxidized G-Rich Motif in the KRAS Promoter
por: Ferino, Annalisa, et al.
Publicado: (2021)

8-Oxoguanine DNA glycosylase 1 selectively modulates ROS-responsive NF-κB targets through recruitment of MSK1 and phosphorylation of RelA/p65 at Ser276
por: Xue, Yaoyao, et al.
Publicado: (2023)

N-Methylpurine DNA Glycosylase and OGG1 DNA Repair Activities: Opposite Associations With Lung Cancer Risk
por: Leitner-Dagan, Yael, et al.
Publicado: (2012)

Human 8-oxoguanine DNA glycosylase gene polymorphism (Ser326Cys) and cancer risk: updated meta-analysis
por: Kang, Sang Wook, et al.
Publicado: (2017)

RELA∙8-Oxoguanine DNA Glycosylase1 Is an Epigenetic Regulatory Complex Coordinating the Hexosamine Biosynthetic Pathway in RSV Infection
por: Xu, Xiaofang, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_m6s1cp2e85kkr473fa16r11fhv