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Phosphorylation of human oxoguanine DNA glycosylase (α-OGG1) modulates its function

Oxoguanine DNA glycosylase (OGG1) initiates the repair of 8-oxoguanine (8-oxoG), a major oxidative DNA base modification that has been directly implicated in cancer and aging. OGG1 functions in the base excision repair pathway, for which a molecular hand-off mechanism has been proposed. To date, onl...

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Detalles Bibliográficos
Autores principales:	Hu, Jingping, Imam, Syed Z., Hashiguchi, Kazunari, de Souza-Pinto, Nadja C., Bohr, Vilhelm A.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1143695/ https://www.ncbi.nlm.nih.gov/pubmed/15942030 http://dx.doi.org/10.1093/nar/gki636

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