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(1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition

To assess if (1→3)-β-D-glucan, a microbial cell wall agent normally present in pollen, has the ability to produce pollenlike response, sensitive persons received a nasal deposition of two doses of (1→3)-β-D-glucan. The percentage of eosinophils and amount of eotaxin were measured in nasal lavage 30...

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Detalles Bibliográficos
Autores principales: Beijer, L., Rylander, R.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1150332/
https://www.ncbi.nlm.nih.gov/pubmed/15770066
http://dx.doi.org/10.1155/MI.2005.50
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author Beijer, L.
Rylander, R.
author_facet Beijer, L.
Rylander, R.
author_sort Beijer, L.
collection PubMed
description To assess if (1→3)-β-D-glucan, a microbial cell wall agent normally present in pollen, has the ability to produce pollenlike response, sensitive persons received a nasal deposition of two doses of (1→3)-β-D-glucan. The percentage of eosinophils and amount of eotaxin were measured in nasal lavage 30 minutes and 24 hours after challenge. No effect could be demonstrated. The absence of an inflammatory response after (1→3)-β-D-glucan application confirms earlier findings in inhalation studies.
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spelling pubmed-11503322006-07-25 (1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition Beijer, L. Rylander, R. Mediators Inflamm Short Communication To assess if (1→3)-β-D-glucan, a microbial cell wall agent normally present in pollen, has the ability to produce pollenlike response, sensitive persons received a nasal deposition of two doses of (1→3)-β-D-glucan. The percentage of eosinophils and amount of eotaxin were measured in nasal lavage 30 minutes and 24 hours after challenge. No effect could be demonstrated. The absence of an inflammatory response after (1→3)-β-D-glucan application confirms earlier findings in inhalation studies. Hindawi Publishing Corporation 2005-02-24 /pmc/articles/PMC1150332/ /pubmed/15770066 http://dx.doi.org/10.1155/MI.2005.50 Text en Hindawi Publishing Corporation This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communication
Beijer, L.
Rylander, R.
(1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition
title (1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition
title_full (1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition
title_fullStr (1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition
title_full_unstemmed (1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition
title_short (1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition
title_sort (1→3)-β-d-glucan does not induce acute inflammation after nasal deposition
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1150332/
https://www.ncbi.nlm.nih.gov/pubmed/15770066
http://dx.doi.org/10.1155/MI.2005.50
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