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(1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition
To assess if (1→3)-β-D-glucan, a microbial cell wall agent normally present in pollen, has the ability to produce pollenlike response, sensitive persons received a nasal deposition of two doses of (1→3)-β-D-glucan. The percentage of eosinophils and amount of eotaxin were measured in nasal lavage 30...
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1150332/ https://www.ncbi.nlm.nih.gov/pubmed/15770066 http://dx.doi.org/10.1155/MI.2005.50 |
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author | Beijer, L. Rylander, R. |
author_facet | Beijer, L. Rylander, R. |
author_sort | Beijer, L. |
collection | PubMed |
description | To assess if (1→3)-β-D-glucan, a microbial cell wall agent normally present in pollen, has the ability to produce pollenlike response, sensitive persons received a nasal deposition of two doses of (1→3)-β-D-glucan. The percentage of eosinophils and amount of eotaxin were measured in nasal lavage 30 minutes and 24 hours after challenge. No effect could be demonstrated. The absence of an inflammatory response after (1→3)-β-D-glucan application confirms earlier findings in inhalation studies. |
format | Text |
id | pubmed-1150332 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-11503322006-07-25 (1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition Beijer, L. Rylander, R. Mediators Inflamm Short Communication To assess if (1→3)-β-D-glucan, a microbial cell wall agent normally present in pollen, has the ability to produce pollenlike response, sensitive persons received a nasal deposition of two doses of (1→3)-β-D-glucan. The percentage of eosinophils and amount of eotaxin were measured in nasal lavage 30 minutes and 24 hours after challenge. No effect could be demonstrated. The absence of an inflammatory response after (1→3)-β-D-glucan application confirms earlier findings in inhalation studies. Hindawi Publishing Corporation 2005-02-24 /pmc/articles/PMC1150332/ /pubmed/15770066 http://dx.doi.org/10.1155/MI.2005.50 Text en Hindawi Publishing Corporation This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Short Communication Beijer, L. Rylander, R. (1→3)-β-D-Glucan Does Not Induce Acute Inflammation After Nasal Deposition |
title | (1→3)-β-D-Glucan Does Not Induce Acute
Inflammation After Nasal Deposition |
title_full | (1→3)-β-D-Glucan Does Not Induce Acute
Inflammation After Nasal Deposition |
title_fullStr | (1→3)-β-D-Glucan Does Not Induce Acute
Inflammation After Nasal Deposition |
title_full_unstemmed | (1→3)-β-D-Glucan Does Not Induce Acute
Inflammation After Nasal Deposition |
title_short | (1→3)-β-D-Glucan Does Not Induce Acute
Inflammation After Nasal Deposition |
title_sort | (1→3)-β-d-glucan does not induce acute
inflammation after nasal deposition |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1150332/ https://www.ncbi.nlm.nih.gov/pubmed/15770066 http://dx.doi.org/10.1155/MI.2005.50 |
work_keys_str_mv | AT beijerl 13bdglucandoesnotinduceacuteinflammationafternasaldeposition AT rylanderr 13bdglucandoesnotinduceacuteinflammationafternasaldeposition |