Doxycycline-induced expression of sense and inverted-repeat constructs modulates phosphogluconate mutase (Pgm) gene expression in adult Drosophila melanogaster

BACKGROUND: A tetracycline-regulated (conditional) system for RNA interference (RNAi) would have many practical applications. Such a strategy was developed using RNAi of the gene for phosphogluconate mutase (Pgm). Pgm is a candidate lifespan regulator: Pgm(S) allele frequency is increased by selecti...

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Detalles Bibliográficos
Autores principales: Allikian, Michael J, Deckert-Cruz, Denise, Rose, Michael R, Landis, Gary N, Tower, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC115223/
https://www.ncbi.nlm.nih.gov/pubmed/12049662

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