Characterization of TRZ1, a yeast homolog of the human candidate prostate cancer susceptibility gene ELAC2 encoding tRNase Z

BACKGROUND: In humans, mutation of ELAC2 is associated with an increased risk of prostate cancer. ELAC2 has been shown to have tRNase Z activity and is associated with the γ-tubulin complex. RESULTS: In this work, we show that the yeast homolog of ELAC2, encoded by TRZ1 (tRNase Z 1), is involved gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yang, Beck, Audrey, Davenport, Christina, Chen, Yuan, Shattuck, Donna, Tavtigian, Sean V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156898/
https://www.ncbi.nlm.nih.gov/pubmed/15892892
http://dx.doi.org/10.1186/1471-2199-6-12

Ejemplares similares

Ejemplares similares