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The anti-tumor effect of Apo2L/TRAIL on patient pancreatic adenocarcinomas grown as xenografts in SCID mice
BACKGROUND: Apo2L/TRAIL has considerable promise for cancer therapy based on the fact that this member of the tumor necrosis factor family induces apoptosis in the majority of malignant cells, while normal cells are more resistant. Furthermore, in many cells, when Apo2L/TRAIL is combined with chemot...
Autores principales: | Hylander, Bonnie L, Pitoniak, Rose, Penetrante, Remedios B, Gibbs, John F, Oktay, Dilek, Cheng, Jinrong, Repasky, Elizabeth A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156958/ https://www.ncbi.nlm.nih.gov/pubmed/15943879 http://dx.doi.org/10.1186/1479-5876-3-22 |
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