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Polyamines stimulate the formation of mutagenic 1,N(2)-propanodeoxyguanosine adducts from acetaldehyde

Alcoholic beverage consumption is associated with an increased risk of upper gastrointestinal cancer. Acetaldehyde (AA), the first metabolite of ethanol, is a suspected human carcinogen, but the molecular mechanisms underlying AA carcinogenicity are unclear. In this work, we tested the hypothesis th...

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Detalles Bibliográficos
Autores principales:	Theruvathu, Jacob A., Jaruga, Pawel, Nath, Raghu G., Dizdaroglu, Miral, Brooks, P. J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1156964/ https://www.ncbi.nlm.nih.gov/pubmed/15972793 http://dx.doi.org/10.1093/nar/gki661

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