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The Diamond STING server
Diamond STING is a new version of the STING suite of programs for a comprehensive analysis of a relationship between protein sequence, structure, function and stability. We have added a number of new functionalities by both providing more structure parameters to the STING Database and by improving/e...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2005
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160158/ https://www.ncbi.nlm.nih.gov/pubmed/15980473 http://dx.doi.org/10.1093/nar/gki397 |
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author | Neshich, Goran Borro, Luiz C. Higa, Roberto H. Kuser, Paula R. Yamagishi, Michel E. B. Franco, Eduardo H. Krauchenco, Joao N. Fileto, Renato Ribeiro, André A. Bezerra, George B. P. Velludo, Thiago M. Jimenez, Tomás S. Furukawa, Noboru Teshima, Hirofumi Kitajima, Koji Bava, Abdulla Sarai, Akinori Togawa, Roberto C. Mancini, Adauto L. |
author_facet | Neshich, Goran Borro, Luiz C. Higa, Roberto H. Kuser, Paula R. Yamagishi, Michel E. B. Franco, Eduardo H. Krauchenco, Joao N. Fileto, Renato Ribeiro, André A. Bezerra, George B. P. Velludo, Thiago M. Jimenez, Tomás S. Furukawa, Noboru Teshima, Hirofumi Kitajima, Koji Bava, Abdulla Sarai, Akinori Togawa, Roberto C. Mancini, Adauto L. |
author_sort | Neshich, Goran |
collection | PubMed |
description | Diamond STING is a new version of the STING suite of programs for a comprehensive analysis of a relationship between protein sequence, structure, function and stability. We have added a number of new functionalities by both providing more structure parameters to the STING Database and by improving/expanding the interface for enhanced data handling. The integration among the STING components has also been improved. A new key feature is the ability of the STING server to handle local files containing protein structures (either modeled or not yet deposited to the Protein Data Bank) so that they can be used by the principal STING components: (Java)Protein Dossier ((J)PD) and STING Report. The current capabilities of the new STING version and a couple of biologically relevant applications are described here. We have provided an example where Diamond STING identifies the active site amino acids and folding essential amino acids (both previously determined by experiments) by filtering out all but those residues by selecting the numerical values/ranges for a set of corresponding parameters. This is the fundamental step toward a more interesting endeavor—the prediction of such residues. Diamond STING is freely accessible at and . |
format | Text |
id | pubmed-1160158 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2005 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-11601582005-06-29 The Diamond STING server Neshich, Goran Borro, Luiz C. Higa, Roberto H. Kuser, Paula R. Yamagishi, Michel E. B. Franco, Eduardo H. Krauchenco, Joao N. Fileto, Renato Ribeiro, André A. Bezerra, George B. P. Velludo, Thiago M. Jimenez, Tomás S. Furukawa, Noboru Teshima, Hirofumi Kitajima, Koji Bava, Abdulla Sarai, Akinori Togawa, Roberto C. Mancini, Adauto L. Nucleic Acids Res Article Diamond STING is a new version of the STING suite of programs for a comprehensive analysis of a relationship between protein sequence, structure, function and stability. We have added a number of new functionalities by both providing more structure parameters to the STING Database and by improving/expanding the interface for enhanced data handling. The integration among the STING components has also been improved. A new key feature is the ability of the STING server to handle local files containing protein structures (either modeled or not yet deposited to the Protein Data Bank) so that they can be used by the principal STING components: (Java)Protein Dossier ((J)PD) and STING Report. The current capabilities of the new STING version and a couple of biologically relevant applications are described here. We have provided an example where Diamond STING identifies the active site amino acids and folding essential amino acids (both previously determined by experiments) by filtering out all but those residues by selecting the numerical values/ranges for a set of corresponding parameters. This is the fundamental step toward a more interesting endeavor—the prediction of such residues. Diamond STING is freely accessible at and . Oxford University Press 2005-07-01 2005-06-27 /pmc/articles/PMC1160158/ /pubmed/15980473 http://dx.doi.org/10.1093/nar/gki397 Text en © The Author 2005. Published by Oxford University Press. All rights reserved |
spellingShingle | Article Neshich, Goran Borro, Luiz C. Higa, Roberto H. Kuser, Paula R. Yamagishi, Michel E. B. Franco, Eduardo H. Krauchenco, Joao N. Fileto, Renato Ribeiro, André A. Bezerra, George B. P. Velludo, Thiago M. Jimenez, Tomás S. Furukawa, Noboru Teshima, Hirofumi Kitajima, Koji Bava, Abdulla Sarai, Akinori Togawa, Roberto C. Mancini, Adauto L. The Diamond STING server |
title | The Diamond STING server |
title_full | The Diamond STING server |
title_fullStr | The Diamond STING server |
title_full_unstemmed | The Diamond STING server |
title_short | The Diamond STING server |
title_sort | diamond sting server |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160158/ https://www.ncbi.nlm.nih.gov/pubmed/15980473 http://dx.doi.org/10.1093/nar/gki397 |
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