Cargando…

The Diamond STING server

Diamond STING is a new version of the STING suite of programs for a comprehensive analysis of a relationship between protein sequence, structure, function and stability. We have added a number of new functionalities by both providing more structure parameters to the STING Database and by improving/e...

Descripción completa

Detalles Bibliográficos
Autores principales: Neshich, Goran, Borro, Luiz C., Higa, Roberto H., Kuser, Paula R., Yamagishi, Michel E. B., Franco, Eduardo H., Krauchenco, Joao N., Fileto, Renato, Ribeiro, André A., Bezerra, George B. P., Velludo, Thiago M., Jimenez, Tomás S., Furukawa, Noboru, Teshima, Hirofumi, Kitajima, Koji, Bava, Abdulla, Sarai, Akinori, Togawa, Roberto C., Mancini, Adauto L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160158/
https://www.ncbi.nlm.nih.gov/pubmed/15980473
http://dx.doi.org/10.1093/nar/gki397
_version_ 1782124365054214144
author Neshich, Goran
Borro, Luiz C.
Higa, Roberto H.
Kuser, Paula R.
Yamagishi, Michel E. B.
Franco, Eduardo H.
Krauchenco, Joao N.
Fileto, Renato
Ribeiro, André A.
Bezerra, George B. P.
Velludo, Thiago M.
Jimenez, Tomás S.
Furukawa, Noboru
Teshima, Hirofumi
Kitajima, Koji
Bava, Abdulla
Sarai, Akinori
Togawa, Roberto C.
Mancini, Adauto L.
author_facet Neshich, Goran
Borro, Luiz C.
Higa, Roberto H.
Kuser, Paula R.
Yamagishi, Michel E. B.
Franco, Eduardo H.
Krauchenco, Joao N.
Fileto, Renato
Ribeiro, André A.
Bezerra, George B. P.
Velludo, Thiago M.
Jimenez, Tomás S.
Furukawa, Noboru
Teshima, Hirofumi
Kitajima, Koji
Bava, Abdulla
Sarai, Akinori
Togawa, Roberto C.
Mancini, Adauto L.
author_sort Neshich, Goran
collection PubMed
description Diamond STING is a new version of the STING suite of programs for a comprehensive analysis of a relationship between protein sequence, structure, function and stability. We have added a number of new functionalities by both providing more structure parameters to the STING Database and by improving/expanding the interface for enhanced data handling. The integration among the STING components has also been improved. A new key feature is the ability of the STING server to handle local files containing protein structures (either modeled or not yet deposited to the Protein Data Bank) so that they can be used by the principal STING components: (Java)Protein Dossier ((J)PD) and STING Report. The current capabilities of the new STING version and a couple of biologically relevant applications are described here. We have provided an example where Diamond STING identifies the active site amino acids and folding essential amino acids (both previously determined by experiments) by filtering out all but those residues by selecting the numerical values/ranges for a set of corresponding parameters. This is the fundamental step toward a more interesting endeavor—the prediction of such residues. Diamond STING is freely accessible at and .
format Text
id pubmed-1160158
institution National Center for Biotechnology Information
language English
publishDate 2005
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-11601582005-06-29 The Diamond STING server Neshich, Goran Borro, Luiz C. Higa, Roberto H. Kuser, Paula R. Yamagishi, Michel E. B. Franco, Eduardo H. Krauchenco, Joao N. Fileto, Renato Ribeiro, André A. Bezerra, George B. P. Velludo, Thiago M. Jimenez, Tomás S. Furukawa, Noboru Teshima, Hirofumi Kitajima, Koji Bava, Abdulla Sarai, Akinori Togawa, Roberto C. Mancini, Adauto L. Nucleic Acids Res Article Diamond STING is a new version of the STING suite of programs for a comprehensive analysis of a relationship between protein sequence, structure, function and stability. We have added a number of new functionalities by both providing more structure parameters to the STING Database and by improving/expanding the interface for enhanced data handling. The integration among the STING components has also been improved. A new key feature is the ability of the STING server to handle local files containing protein structures (either modeled or not yet deposited to the Protein Data Bank) so that they can be used by the principal STING components: (Java)Protein Dossier ((J)PD) and STING Report. The current capabilities of the new STING version and a couple of biologically relevant applications are described here. We have provided an example where Diamond STING identifies the active site amino acids and folding essential amino acids (both previously determined by experiments) by filtering out all but those residues by selecting the numerical values/ranges for a set of corresponding parameters. This is the fundamental step toward a more interesting endeavor—the prediction of such residues. Diamond STING is freely accessible at and . Oxford University Press 2005-07-01 2005-06-27 /pmc/articles/PMC1160158/ /pubmed/15980473 http://dx.doi.org/10.1093/nar/gki397 Text en © The Author 2005. Published by Oxford University Press. All rights reserved
spellingShingle Article
Neshich, Goran
Borro, Luiz C.
Higa, Roberto H.
Kuser, Paula R.
Yamagishi, Michel E. B.
Franco, Eduardo H.
Krauchenco, Joao N.
Fileto, Renato
Ribeiro, André A.
Bezerra, George B. P.
Velludo, Thiago M.
Jimenez, Tomás S.
Furukawa, Noboru
Teshima, Hirofumi
Kitajima, Koji
Bava, Abdulla
Sarai, Akinori
Togawa, Roberto C.
Mancini, Adauto L.
The Diamond STING server
title The Diamond STING server
title_full The Diamond STING server
title_fullStr The Diamond STING server
title_full_unstemmed The Diamond STING server
title_short The Diamond STING server
title_sort diamond sting server
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160158/
https://www.ncbi.nlm.nih.gov/pubmed/15980473
http://dx.doi.org/10.1093/nar/gki397
work_keys_str_mv AT neshichgoran thediamondstingserver
AT borroluizc thediamondstingserver
AT higarobertoh thediamondstingserver
AT kuserpaular thediamondstingserver
AT yamagishimicheleb thediamondstingserver
AT francoeduardoh thediamondstingserver
AT krauchencojoaon thediamondstingserver
AT filetorenato thediamondstingserver
AT ribeiroandrea thediamondstingserver
AT bezerrageorgebp thediamondstingserver
AT velludothiagom thediamondstingserver
AT jimeneztomass thediamondstingserver
AT furukawanoboru thediamondstingserver
AT teshimahirofumi thediamondstingserver
AT kitajimakoji thediamondstingserver
AT bavaabdulla thediamondstingserver
AT saraiakinori thediamondstingserver
AT togawarobertoc thediamondstingserver
AT manciniadautol thediamondstingserver
AT neshichgoran diamondstingserver
AT borroluizc diamondstingserver
AT higarobertoh diamondstingserver
AT kuserpaular diamondstingserver
AT yamagishimicheleb diamondstingserver
AT francoeduardoh diamondstingserver
AT krauchencojoaon diamondstingserver
AT filetorenato diamondstingserver
AT ribeiroandrea diamondstingserver
AT bezerrageorgebp diamondstingserver
AT velludothiagom diamondstingserver
AT jimeneztomass diamondstingserver
AT furukawanoboru diamondstingserver
AT teshimahirofumi diamondstingserver
AT kitajimakoji diamondstingserver
AT bavaabdulla diamondstingserver
AT saraiakinori diamondstingserver
AT togawarobertoc diamondstingserver
AT manciniadautol diamondstingserver