GenePath: from mutations to genetic networks and back

GenePath is a web-based application for the analysis of mutant-based experiments and synthesis of genetic networks. Here, we introduce GenePath and describe a number of new approaches, including conflict resolution, handling cyclic pathways, confidence level assignment, what-if analysis and new expe...

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Detalles Bibliográficos
Autores principales: Juvan, Peter, Demsar, Janez, Shaulsky, Gad, Zupan, Blaz
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160187/
https://www.ncbi.nlm.nih.gov/pubmed/15980576
http://dx.doi.org/10.1093/nar/gki426
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author Juvan, Peter
Demsar, Janez
Shaulsky, Gad
Zupan, Blaz
author_facet Juvan, Peter
Demsar, Janez
Shaulsky, Gad
Zupan, Blaz
author_sort Juvan, Peter
collection PubMed
description GenePath is a web-based application for the analysis of mutant-based experiments and synthesis of genetic networks. Here, we introduce GenePath and describe a number of new approaches, including conflict resolution, handling cyclic pathways, confidence level assignment, what-if analysis and new experiment proposal. We illustrate the key concepts using data from a study of adhesion genes in Dictyostelium discoideum and show that GenePath discovered genetic interactions that were ignored in the original publication. GenePath is available at .
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spelling pubmed-11601872005-06-29 GenePath: from mutations to genetic networks and back Juvan, Peter Demsar, Janez Shaulsky, Gad Zupan, Blaz Nucleic Acids Res Article GenePath is a web-based application for the analysis of mutant-based experiments and synthesis of genetic networks. Here, we introduce GenePath and describe a number of new approaches, including conflict resolution, handling cyclic pathways, confidence level assignment, what-if analysis and new experiment proposal. We illustrate the key concepts using data from a study of adhesion genes in Dictyostelium discoideum and show that GenePath discovered genetic interactions that were ignored in the original publication. GenePath is available at . Oxford University Press 2005-07-01 2005-06-27 /pmc/articles/PMC1160187/ /pubmed/15980576 http://dx.doi.org/10.1093/nar/gki426 Text en © The Author 2005. Published by Oxford University Press. All rights reserved
spellingShingle Article
Juvan, Peter
Demsar, Janez
Shaulsky, Gad
Zupan, Blaz
GenePath: from mutations to genetic networks and back
title GenePath: from mutations to genetic networks and back
title_full GenePath: from mutations to genetic networks and back
title_fullStr GenePath: from mutations to genetic networks and back
title_full_unstemmed GenePath: from mutations to genetic networks and back
title_short GenePath: from mutations to genetic networks and back
title_sort genepath: from mutations to genetic networks and back
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160187/
https://www.ncbi.nlm.nih.gov/pubmed/15980576
http://dx.doi.org/10.1093/nar/gki426
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AT demsarjanez genepathfrommutationstogeneticnetworksandback
AT shaulskygad genepathfrommutationstogeneticnetworksandback
AT zupanblaz genepathfrommutationstogeneticnetworksandback

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