GBA server: EST-based digital gene expression profiling

Expressed Sequence Tag-based gene expression profiling can be used to discover functionally associated genes on a large scale. Currently available web servers and tools focus on finding differentially expressed genes in different samples or tissues rather than finding co-expressed genes. To fill thi...

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Detalles Bibliográficos
Autores principales: Wu, Xin, Walker, Michael G., Luo, Jingchu, Wei, Liping
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160240/
https://www.ncbi.nlm.nih.gov/pubmed/15980560
http://dx.doi.org/10.1093/nar/gki480
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author Wu, Xin
Walker, Michael G.
Luo, Jingchu
Wei, Liping
author_facet Wu, Xin
Walker, Michael G.
Luo, Jingchu
Wei, Liping
author_sort Wu, Xin
collection PubMed
description Expressed Sequence Tag-based gene expression profiling can be used to discover functionally associated genes on a large scale. Currently available web servers and tools focus on finding differentially expressed genes in different samples or tissues rather than finding co-expressed genes. To fill this gap, we have developed a web server that implements the GBA (Guilt-by-Association) co-expression algorithm, which has been successfully used in finding disease-related genes. We have also annotated UniGene clusters with links to several important databases such as GO, KEGG, OMIM, Gene, IPI and HomoloGene. The GBA server can be accessed and downloaded at .
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spelling pubmed-11602402005-06-29 GBA server: EST-based digital gene expression profiling Wu, Xin Walker, Michael G. Luo, Jingchu Wei, Liping Nucleic Acids Res Article Expressed Sequence Tag-based gene expression profiling can be used to discover functionally associated genes on a large scale. Currently available web servers and tools focus on finding differentially expressed genes in different samples or tissues rather than finding co-expressed genes. To fill this gap, we have developed a web server that implements the GBA (Guilt-by-Association) co-expression algorithm, which has been successfully used in finding disease-related genes. We have also annotated UniGene clusters with links to several important databases such as GO, KEGG, OMIM, Gene, IPI and HomoloGene. The GBA server can be accessed and downloaded at . Oxford University Press 2005-07-01 2005-06-27 /pmc/articles/PMC1160240/ /pubmed/15980560 http://dx.doi.org/10.1093/nar/gki480 Text en © The Author 2005. Published by Oxford University Press. All rights reserved
spellingShingle Article
Wu, Xin
Walker, Michael G.
Luo, Jingchu
Wei, Liping
GBA server: EST-based digital gene expression profiling
title GBA server: EST-based digital gene expression profiling
title_full GBA server: EST-based digital gene expression profiling
title_fullStr GBA server: EST-based digital gene expression profiling
title_full_unstemmed GBA server: EST-based digital gene expression profiling
title_short GBA server: EST-based digital gene expression profiling
title_sort gba server: est-based digital gene expression profiling
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160240/
https://www.ncbi.nlm.nih.gov/pubmed/15980560
http://dx.doi.org/10.1093/nar/gki480
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AT walkermichaelg gbaserverestbaseddigitalgeneexpressionprofiling
AT luojingchu gbaserverestbaseddigitalgeneexpressionprofiling
AT weiliping gbaserverestbaseddigitalgeneexpressionprofiling

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