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SCANMOT: searching for similar sequences using a simultaneous scan of multiple sequence motifs

Establishment of similarities between proteins is very important for the study of the relationship between sequence, structure and function and for the analysis of evolutionary relationships. Motif-based search methods play a crucial role in establishing the connections between proteins that are par...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Saikat, Anand, A. Prem, Bhardwaj, Nitin, Pugalenthi, Ganesan, Sowdhamini, R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160253/
https://www.ncbi.nlm.nih.gov/pubmed/15980468
http://dx.doi.org/10.1093/nar/gki493
Descripción
Sumario:Establishment of similarities between proteins is very important for the study of the relationship between sequence, structure and function and for the analysis of evolutionary relationships. Motif-based search methods play a crucial role in establishing the connections between proteins that are particularly useful for distant relationships. This paper reports SCANMOT, a web-based server that searches for similarities between proteins by simultaneous matching of multiple motifs. SCANMOT searches for similar sequences in entire sequence databases using multiple conserved regions and utilizes inter-motif spacing as restraints. The SCANMOT server is available via .