Cargando…

PTPRC (CD45) is not associated with multiple sclerosis in a large cohort of German patients

BACKGROUND: Since contradictory results have been reported, we reanalysed the 77C→G transition in exon 4 of the protein-tyrosine phosphatase receptor-type C (PTPRC also known as CD45) in a large cohort of German MS patients and controls. Different isoforms of the protein are expressed, depending on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Miterski, Bianca, Sindern, Eckhart, Haupts, Michael, Schimrigk, Sebastian, Epplen, Joerg T
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC116441/ https://www.ncbi.nlm.nih.gov/pubmed/12028593 http://dx.doi.org/10.1186/1471-2350-3-3

Ejemplares similares

An extended association screen in multiple sclerosis using 202 microsatellite markers targeting apoptosis-related genes does not reveal new predisposing factors
por: Gödde, René, et al.
Publicado: (2005)

Protein tyrosine phosphatase receptor type C (PTPRC or CD45)
por: Al Barashdi, Maryam Ahmed, et al.
Publicado: (2021)

C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
por: Landskron, Johannes, et al.
Publicado: (2017)

Faith as a Resource in Patients with Multiple Sclerosis Is Associated with a Positive Interpretation of Illness and Experience of Gratitude/Awe
por: Büssing, Arndt, et al.
Publicado: (2013)

Experience of gratitude, awe and beauty in life among patients with multiple sclerosis and psychiatric disorders
por: Büssing, Arndt, et al.
Publicado: (2014)

PTPRG and PTPRC modulate nilotinib response in chronic myeloid leukemia cells
por: Drube, Julia, et al.
Publicado: (2018)

Replication of Association of the PTPRC Gene With Response to Anti–Tumor Necrosis Factor Therapy in a Large UK Cohort
por: Plant, Darren, et al.
Publicado: (2012)

PTPRC functions as a prognosis biomarker in the tumor microenvironment of cutaneous melanoma
por: Li, Xuemei, et al.
Publicado: (2023)

Complex genetic predisposition in adult and juvenile rheumatoid arthritis
por: Miterski, Bianca, et al.
Publicado: (2004)

Upregulation of PTPRC and Interferon Response Pathways in HIV-1 Seroconverters Prior to Infection
por: Li, Yunqi, et al.
Publicado: (2023)

CCR2 and PTPRC are regulators of tumor microenvironment and potential prognostic biomarkers of lung adenocarcinoma
por: Wei, Jie, et al.
Publicado: (2021)

Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis
por: Hellwig, Kerstin, et al.
Publicado: (2006)

Uncover diagnostic immunity/hypoxia/ferroptosis/epithelial mesenchymal transformation-related CCR5, CD86, CD8A, ITGAM, and PTPRC in kidney transplantation patients with allograft rejection
por: He, Long, et al.
Publicado: (2022)

Association of variation in the LAMA3 gene, encoding the alpha-chain of laminin 5, with atopic dermatitis in a German case–control cohort
por: Stemmler, Susanne, et al.
Publicado: (2014)

TRAF1/C5 but Not PTPRC Variants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy
por: Canhão, Helena, et al.
Publicado: (2015)

Salivary IL-1ß as an Objective Measure for Fatigue in Multiple Sclerosis?
por: Hanken, Katrin, et al.
Publicado: (2018)

Multiomics to investigate the mechanisms contributing to repression of PTPRC and SOCS2 in pediatric T‐ALL: Focus on miR‐363‐3p and promoter methylation
por: Drobna‐Śledzińska, Monika, et al.
Publicado: (2022)

Genomic NGFB variation and multiple sclerosis in a case control study
por: Akkad, Denis A, et al.
Publicado: (2008)

Cardiotoxicity of Mitoxantrone Treatment in a German Cohort of 639 Multiple Sclerosis Patients
por: Fleischer, Vinzenz, et al.
Publicado: (2014)

Preference-based Health status in a German outpatient cohort with multiple sclerosis
por: Reese, Jens Peter, et al.
Publicado: (2013)

PTPRC promoted CD8+ T cell mediated tumor immunity and drug sensitivity in breast cancer: based on pan-cancer analysis and artificial intelligence modeling of immunogenic cell death-based drug sensitivity stratification
por: Li, Pengping, et al.
Publicado: (2023)

45 years German Society of Biological Psychiatry (DGBP)
por: Riederer, P., et al.
Publicado: (2023)

Reasons to switch: a noninterventional study evaluating immunotherapy switches in a large German multicentre cohort of patients with relapsing-remitting multiple sclerosis
por: Mäurer, Mathias, et al.
Publicado: (2019)

Optic neuritis in German children: clinical findings and association with multiple sclerosis
por: Tonagel, Felix, et al.
Publicado: (2020)

Increased serum levels of fractalkine and mobilisation of CD34(+)CD45(−) endothelial progenitor cells in systemic sclerosis
por: Benyamine, Audrey, et al.
Publicado: (2017)

Differential Expression of CD45RO and CD45RA in Bovine T Cells
por: Kandel, Anmol, et al.
Publicado: (2022)

Correction to: Optic neuritis in German children: clinical findings and association with multiple sclerosis
por: Tonagel, Felix, et al.
Publicado: (2021)

The German Multiple Sclerosis and Pregnancy Registry: rationale, objective, design, and first results
por: Thiel, Sandra, et al.
Publicado: (2021)

Regulation of CD45 phosphatase by oncogenic ALK in anaplastic large cell lymphoma
por: Mura, Giulia, et al.
Publicado: (2023)

CD45RA and CD45RBhigh expression induced by thymic selection events
Publicado: (1992)

Analysis of PDE6D and PDE6G genes for generalised progressive retinal atrophy (gPRA) mutations in dogs
por: Dekomien, Gabriele, et al.
Publicado: (2003)

Combinations of Susceptibility Genes Are Associated with Higher Risk for Multiple Sclerosis and Imply Disease Course Specificity
por: Akkad, Denis A., et al.
Publicado: (2015)

Health behaviors of people with multiple sclerosis and its associations with MS related outcomes: a German clinical cohort
por: Goldin, Katharina, et al.
Publicado: (2023)

Factors associated with depressive mood at the onset of multiple sclerosis - an analysis of 781 patients of the German NationMS cohort
por: Salmen, Anke, et al.
Publicado: (2023)

Involvement of CD8(+) T Cells in Multiple Sclerosis
por: Salou, Marion, et al.
Publicado: (2015)

German translation, cultural adaptation and validation of the unidimensional self-efficacy scale for multiple sclerosis
por: Seebacher, Barbara, et al.
Publicado: (2021)

Application of Statistical Methods for Central Statistical Monitoring and Implementations on the German Multiple Sclerosis Registry
por: Fneish, Firas, et al.
Publicado: (2023)

Differential susceptibility of C57BL/6NCr and B6.Cg-Ptprc(a )mice to commensal bacteria after whole body irradiation in translational bone marrow transplant studies
por: Duran-Struuck, Raimon, et al.
Publicado: (2008)

CD4+CD45RA+ T-cells from early diffuse systemic sclerosis patients produce high levels of interleukin-17
por: van Bon, Lenny, et al.
Publicado: (2011)

mtDNA nt13708A Variant Increases the Risk of Multiple Sclerosis
por: Yu, Xinhua, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_cou9c17nv27q3bpdhqk2f2plqk