Potential genetic modifiers of the cystic fibrosis intestinal inflammatory phenotype on mouse chromosomes 1, 9, and 10

BACKGROUND: Although cystic fibrosis is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, the severity of disease is highly variable indicating the influence of modifier genes. The intestines of Cftr deficient mice (CF mice: Cftr(tm1Unc)) are prone to obstru...

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Detalles Bibliográficos
Autores principales: Norkina, Oxana, De Lisle, Robert C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166548/
https://www.ncbi.nlm.nih.gov/pubmed/15921521
http://dx.doi.org/10.1186/1471-2156-6-29

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