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TRIM5α selectively binds a restriction-sensitive retroviral capsid
TRIM5 is a potent retrovirus inhibitor that targets viruses bearing particular capsid (CA) residues. In most primate species, retroviral restriction requires the C-terminal SPRY domain unique to the α-isoform of TRIM5, but the mechanism by which susceptible viruses are recognized and targeted for re...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1166576/ https://www.ncbi.nlm.nih.gov/pubmed/15967037 http://dx.doi.org/10.1186/1742-4690-2-40 |