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RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs

BACKGROUND: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein's function than paralogous sequences (that diverged by gene duplication). The utility of phylogenetic information in...

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Detalles Bibliográficos
Autores principales: Zmasek, Christian M, Eddy, Sean R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC116988/
https://www.ncbi.nlm.nih.gov/pubmed/12028595
http://dx.doi.org/10.1186/1471-2105-3-14

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