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RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
BACKGROUND: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein's function than paralogous sequences (that diverged by gene duplication). The utility of phylogenetic information in...
Autores principales: | Zmasek, Christian M, Eddy, Sean R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC116988/ https://www.ncbi.nlm.nih.gov/pubmed/12028595 http://dx.doi.org/10.1186/1471-2105-3-14 |
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