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RNA elements required for RNA recombination function as replication enhancers in vitro and in vivo in a plus-strand RNA virus.
RNA replication requires cis-acting elements to recruit the viral RNA-dependent RNA polymerase (RdRp) and facilitate de novo initiation of complementary strand synthesis. Hairpins that are hot spots for recombination in the genomic RNA of turnip crinkle virus (TCV) and satellite (sat)-RNA C, a paras...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1171632/ https://www.ncbi.nlm.nih.gov/pubmed/10523308 http://dx.doi.org/10.1093/emboj/18.20.5653 |