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Mammalian enzymes for preventing transcriptional errors caused by oxidative damage

8-Oxo-7,8-dihydroguanine (8-oxoGua) is produced in cells by reactive oxygen species normally formed during cellular metabolic processes. This oxidized base can pair with both adenine and cytosine, and thus the existence of this base in messenger RNA would cause translational errors. The MutT protein...

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Detalles Bibliográficos
Autores principales:	Ishibashi, Toru, Hayakawa, Hiroshi, Ito, Riyoko, Miyazawa, Masayuki, Yamagata, Yuriko, Sekiguchi, Mutsuo
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174896/ https://www.ncbi.nlm.nih.gov/pubmed/16002790 http://dx.doi.org/10.1093/nar/gki682

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