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Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks
Homologous recombination (HR) deficient cells are sensitive to methyl methanesulfonate (MMS). HR is usually involved in the repair of DNA double-strand breaks (DSBs) in Saccharomyces cerevisiae implying that MMS somehow induces DSBs in vivo. Indeed there is evidence, based on pulsed-field gel electr...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
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Oxford University Press
2005
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174933/ https://www.ncbi.nlm.nih.gov/pubmed/16009812 http://dx.doi.org/10.1093/nar/gki681 |
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por Lundin, Cecilia, North, Matthew, Erixon, Klaus, Walters, Kevin, Jenssen, Dag, Goldman, Alastair S. H., Helleday, Thomas
Publicado 2012
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Publicado 2012
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Online
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