Cargando…

The utility of pathway selective estrogen receptor ligands that inhibit nuclear factor-κB transcriptional activity in models of rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory disease that produces synovial proliferation and joint erosions. The pathologic lesions of RA are driven through the production of inflammatory mediators in the synovium mediated, in part, by the transcription factor NF-κB. We have identified a non...

Descripción completa

Detalles Bibliográficos
Autores principales:	Keith, James C, Albert, Leo M, Leathurby, Yelena, Follettie, Max, Wang, Lili, Borges-Marcucci, Lisa, Chadwick, Christopher C, Steffan, Robert J, Harnish, Douglas C
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2005
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174937/ https://www.ncbi.nlm.nih.gov/pubmed/15899029 http://dx.doi.org/10.1186/ar1692

Ejemplares similares

A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat
por: Keith, James C, et al.
Publicado: (2005)

Integrins and their ligands in rheumatoid arthritis
por: Lowin, Torsten, et al.
Publicado: (2011)

Anti-receptor activator of nuclear factor κB ligand antibody treatment increases osteoclastogenesis-promoting IL-8 in patients with rheumatoid arthritis
por: Morita, Takayoshi, et al.
Publicado: (2019)

Cancer Morbidity in Rheumatoid Arthritis: Role of Estrogen Metabolites
por: Khan, Wahid Ali, et al.
Publicado: (2013)

Receptor activator for nuclear factor-κB ligand signaling promotes progesterone-mediated estrogen-induced mammary carcinogenesis
por: Boopalan, Thiyagarajan, et al.
Publicado: (2015)

Ligands specify estrogen receptor alpha nuclear localization and degradation
por: Kocanova, Silvia, et al.
Publicado: (2010)

Correlation of nuclear factor-κB, regulatory T cell and transforming growth factor β with rheumatoid arthritis
por: Sun, You, et al.
Publicado: (2017)

Plumbagin relieves rheumatoid arthritis through nuclear factor kappa-B (NF-κB) pathway
por: Shu, Chang, et al.
Publicado: (2022)

Soluble Fas ligand inhibits angiogenesis in rheumatoid arthritis
por: Kim, Wan-Uk, et al.
Publicado: (2007)

Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis
por: Lee, Sung-Ji, et al.
Publicado: (2011)

Iguratimod promotes transformation of mononuclear macrophages in elderly patients with rheumatoid arthritis by nuclear factor-κB pathway
por: Liu, Sha, et al.
Publicado: (2021)

Rheumatoid Arthritis
por: Follmar, Keith E., et al.
Publicado: (2013)

Estrogen Protects Articular Cartilage by Downregulating ASIC1a in Rheumatoid Arthritis
por: Hang, Xiaoyu, et al.
Publicado: (2021)

Expression of osteoprotegerin and its ligands, RANKL and TRAIL, in rheumatoid arthritis
por: Remuzgo-Martínez, Sara, et al.
Publicado: (2016)

Review of Biosimilar Trials and Data on Adalimumab in Rheumatoid Arthritis
por: Zhao, Sizheng, et al.
Publicado: (2018)

Review of Biosimilar Trials and Data on Etanercept in Rheumatoid Arthritis
por: Chadwick, Laura, et al.
Publicado: (2018)

Estrogen antagonizes ASIC1a-induced chondrocyte mitochondrial stress in rheumatoid arthritis
por: Zai, Zhuoyan, et al.
Publicado: (2022)

Nuclear Factor kappa B (NF-κB) Targeted Self-Assembled Nanoparticles Loaded with Methotrexate for Treatment of Rheumatoid Arthritis
por: Li, Xiong, et al.
Publicado: (2019)

The role of RANK ligand/OPG system in bone erosions in rheumatoid arthritis
por: Geusens, Piet
Publicado: (2012)

RHEUMATOID FACTOR AND THE PATHOGENESIS OF RHEUMATOID ARTHRITIS
por: Mellors, Robert C., et al.
Publicado: (1961)

The Neuropathies of Rheumatoid Arthritis
por: Pallis, C. A.
Publicado: (1966)

Biomarkers in Rheumatoid Arthritis
por: Shapiro, Samantha C
Publicado: (2021)

Receptor activator of nuclear factor kappa-B ligand (RANKL) but not sclerostin or gene polymorphisms is related to joint destruction in early rheumatoid arthritis
por: Boman, Antonia, et al.
Publicado: (2017)

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis
por: Brown, Keith D, et al.
Publicado: (2008)

Negative regulation of NF-κB and its involvement in rheumatoid arthritis
por: van Loo, Geert, et al.
Publicado: (2011)

Autologous tolerogenic dendritic cells for rheumatoid and inflammatory arthritis
por: Bell, G M, et al.
Publicado: (2017)

Effects of antibody to receptor activator of nuclear factor κ-B ligand on inflammation and cartilage degradation in collagen antibody-induced arthritis in mice
por: Funato, Sakie, et al.
Publicado: (2014)

Prolactin blocks the expression of receptor activator of nuclear factor κB ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis
por: Ledesma-Colunga, Maria G., et al.
Publicado: (2017)

Chrysotherapy in the Treatment of Rheumatoid Arthritis
por: Crawford, J. C. C.
Publicado: (1937)

Expression of Lectin-Like Transcript 1, the Ligand for CD161, in Rheumatoid Arthritis
por: Chalan, Paulina, et al.
Publicado: (2015)

Enhanced expression of mRNA for nuclear factor κB1 (p50) in CD34+ cells of the bone marrow in rheumatoid arthritis
por: Hirohata, Shunsei, et al.
Publicado: (2006)

Elevated microRNA-145-5p increases matrix metalloproteinase-9 by activating the nuclear factor-κB pathway in rheumatoid arthritis
por: Wang, Xiaoxue, et al.
Publicado: (2019)

NF-κB signaling in rheumatoid arthritis with focus on fibroblast-like synoviocytes
por: Nejatbakhsh Samimi, Leila, et al.
Publicado: (2020)

Estrogen downregulates TAK1 expression in human fibroblast-like synoviocytes and in a rheumatoid arthritis model
por: Li, Xi, et al.
Publicado: (2022)

Potential role and mechanism of IFN-gamma inducible protein-10 on receptor activator of nuclear factor kappa-B ligand (RANKL) expression in rheumatoid arthritis
por: Lee, Eun Young, et al.
Publicado: (2011)

Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis
por: van Nieuwenhuijze, Annemarie E. M., et al.
Publicado: (2015)

Trends of rheumatoid arthritis monitorization in Romania
por: Mogoşan, C, et al.
Publicado: (2010)

Modern Management of Rheumatoid Arthritis
por: Huskisson, E. C., et al.
Publicado: (1978)

Increased interleukin-17 production via a phosphoinositide 3-kinase/Akt and nuclear factor κB-dependent pathway in patients with rheumatoid arthritis
por: Kim, Kyoung-Woon, et al.
Publicado: (2005)

Analysis of TNFAIP3, a feedback inhibitor of nuclear factor-κB and the neighbor intergenic 6q23 region in rheumatoid arthritis susceptibility
por: Dieguez-Gonzalez, Rebeca, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_gaquopmjgoq9ktr4gr5sk0ldct